/* ============================================================
   VetDrugRef - Veterinary Drug Reference PWA
   Professional Medical UI Stylesheet
   ============================================================ */

/* ---- CSS Custom Properties (Light Theme) ---- */
:root {
  /* Primary palette */
  --color-primary: #0d6e8a;
  --color-primary-dark: #095068;
  --color-primary-light: #1a9bc0;
  --color-primary-bg: #e6f4f8;
  --color-accent: #10a37f;
  --color-accent-dark: #0b7a5e;

  /* Neutrals */
  --color-bg: #f0f4f8;
  --color-surface: #ffffff;
  --color-surface-alt: #f7f9fc;
  --color-border: #d4dce6;
  --color-border-light: #e8edf3;
  --color-text: #1a2332;
  --color-text-secondary: #5a6a7e;
  --color-text-muted: #8a96a6;

  /* Severity system */
  --severity-contraindicated: #dc2626;
  --severity-contraindicated-bg: #fef2f2;
  --severity-major: #ea580c;
  --severity-major-bg: #fff7ed;
  --severity-moderate: #ca8a04;
  --severity-moderate-bg: #fefce8;
  --severity-minor: #2563eb;
  --severity-minor-bg: #eff6ff;
  --severity-safe: #16a34a;
  --severity-safe-bg: #f0fdf4;

  /* Status colors */
  --color-success: #16a34a;
  --color-warning: #ca8a04;
  --color-danger: #dc2626;
  --color-info: #2563eb;

  /* Shadows */
  --shadow-sm: 0 1px 2px rgba(0, 0, 0, 0.06);
  --shadow-md: 0 4px 12px rgba(0, 0, 0, 0.08);
  --shadow-lg: 0 8px 24px rgba(0, 0, 0, 0.12);
  --shadow-card: 0 2px 8px rgba(0, 0, 0, 0.06);

  /* Typography */
  --font-family: -apple-system, BlinkMacSystemFont, 'Segoe UI', Roboto, 'Helvetica Neue', Arial, sans-serif;
  --font-mono: 'SF Mono', 'Fira Code', 'Fira Mono', 'Roboto Mono', monospace;
  --font-size-base: 16px;
  --font-size-sm: 0.875rem;
  --font-size-xs: 0.75rem;
  --font-size-lg: 1.125rem;
  --font-size-xl: 1.25rem;
  --font-size-2xl: 1.5rem;
  --font-size-3xl: 1.875rem;

  /* Spacing */
  --spacing-xs: 4px;
  --spacing-sm: 8px;
  --spacing-md: 16px;
  --spacing-lg: 24px;
  --spacing-xl: 32px;
  --spacing-2xl: 48px;

  /* Layout */
  --sidebar-width: 260px;
  --patient-panel-height: auto;
  --bottom-nav-height: 64px;
  --header-height: 56px;
  --border-radius: 8px;
  --border-radius-lg: 12px;
  --border-radius-sm: 4px;

  /* Transitions */
  --transition-fast: 150ms ease;
  --transition-base: 250ms ease;
}

/* ---- Dark Theme ---- */
[data-theme="dark"] {
  --color-primary: #22a8cc;
  --color-primary-dark: #0d6e8a;
  --color-primary-light: #3fc2e0;
  --color-primary-bg: #0d2a35;
  --color-accent: #34d399;
  --color-accent-dark: #10a37f;

  --color-bg: #0f1419;
  --color-surface: #1a2332;
  --color-surface-alt: #1e2a3a;
  --color-border: #2d3d50;
  --color-border-light: #253040;
  --color-text: #e8ecf0;
  --color-text-secondary: #a0aec0;
  --color-text-muted: #6b7b8f;

  --severity-contraindicated-bg: #2a1010;
  --severity-major-bg: #2a1a0a;
  --severity-moderate-bg: #2a2510;
  --severity-minor-bg: #0f1a2e;
  --severity-safe-bg: #0a2a14;

  --shadow-sm: 0 1px 2px rgba(0, 0, 0, 0.3);
  --shadow-md: 0 4px 12px rgba(0, 0, 0, 0.4);
  --shadow-lg: 0 8px 24px rgba(0, 0, 0, 0.5);
  --shadow-card: 0 2px 8px rgba(0, 0, 0, 0.3);
}

/* ---- Font Size Adjustment ---- */
[data-fontsize="small"] { --font-size-base: 14px; }
[data-fontsize="medium"] { --font-size-base: 16px; }
[data-fontsize="large"] { --font-size-base: 18px; }
[data-fontsize="xlarge"] { --font-size-base: 20px; }

/* ---- Reset & Base ---- */
*, *::before, *::after {
  box-sizing: border-box;
  margin: 0;
  padding: 0;
}

html {
  font-size: var(--font-size-base);
  -webkit-text-size-adjust: 100%;
  scroll-behavior: smooth;
}

body {
  font-family: var(--font-family);
  background-color: var(--color-bg);
  color: var(--color-text);
  line-height: 1.6;
  min-height: 100vh;
  overflow-x: hidden;
  -webkit-font-smoothing: antialiased;
}

a {
  color: var(--color-primary);
  text-decoration: none;
}
a:hover { text-decoration: underline; }

h1, h2, h3, h4, h5 {
  line-height: 1.3;
  font-weight: 600;
}

h1 { font-size: var(--font-size-3xl); }
h2 { font-size: var(--font-size-2xl); }
h3 { font-size: var(--font-size-xl); }
h4 { font-size: var(--font-size-lg); }

/* ---- App Layout ---- */
.app-layout {
  display: flex;
  min-height: 100vh;
}

/* ---- Sidebar (Desktop) ---- */
.sidebar {
  display: none;
  width: var(--sidebar-width);
  background: var(--color-surface);
  border-right: 1px solid var(--color-border);
  position: fixed;
  top: 0;
  left: 0;
  bottom: 0;
  z-index: 100;
  overflow-y: auto;
  flex-shrink: 0;
}

.sidebar-header {
  padding: var(--spacing-lg);
  border-bottom: 1px solid var(--color-border);
}

.sidebar-logo {
  display: flex;
  align-items: center;
  gap: var(--spacing-sm);
}

.sidebar-logo .logo-icon {
  width: 36px;
  height: 36px;
  background: var(--color-primary);
  border-radius: var(--border-radius);
  display: flex;
  align-items: center;
  justify-content: center;
  color: white;
  font-weight: 700;
  font-size: var(--font-size-lg);
}

.sidebar-logo h1 {
  font-size: var(--font-size-lg);
  color: var(--color-primary);
}

.sidebar-logo .subtitle {
  font-size: var(--font-size-xs);
  color: var(--color-text-muted);
  display: block;
}

.sidebar-nav {
  padding: var(--spacing-md) 0;
}

.sidebar-nav .nav-section-title {
  padding: var(--spacing-sm) var(--spacing-lg);
  font-size: var(--font-size-xs);
  font-weight: 600;
  text-transform: uppercase;
  letter-spacing: 0.05em;
  color: var(--color-text-muted);
  margin-top: var(--spacing-sm);
}

.sidebar-nav a {
  display: flex;
  align-items: center;
  gap: var(--spacing-sm);
  padding: 10px var(--spacing-lg);
  color: var(--color-text-secondary);
  font-size: var(--font-size-sm);
  font-weight: 500;
  transition: all var(--transition-fast);
  border-left: 3px solid transparent;
  text-decoration: none;
}

.sidebar-nav a:hover {
  background: var(--color-primary-bg);
  color: var(--color-primary);
  text-decoration: none;
}

.sidebar-nav a.active {
  background: var(--color-primary-bg);
  color: var(--color-primary);
  border-left-color: var(--color-primary);
  font-weight: 600;
}

.sidebar-nav a .nav-icon {
  width: 20px;
  text-align: center;
  font-size: var(--font-size-base);
}

.sidebar-footer {
  padding: var(--spacing-md) var(--spacing-lg);
  border-top: 1px solid var(--color-border);
  position: absolute;
  bottom: 0;
  width: 100%;
  background: var(--color-surface);
}

.online-indicator {
  display: flex;
  align-items: center;
  gap: var(--spacing-sm);
  font-size: var(--font-size-xs);
  color: var(--color-text-muted);
}

.online-dot {
  width: 8px;
  height: 8px;
  border-radius: 50%;
  background: var(--color-success);
}

.online-dot.offline {
  background: var(--color-danger);
}

/* ---- Main Content Area ---- */
.main-content {
  flex: 1;
  min-height: 100vh;
  padding-bottom: calc(var(--bottom-nav-height) + var(--spacing-md));
}

/* ---- Mobile Header ---- */
.mobile-header {
  display: flex;
  align-items: center;
  justify-content: space-between;
  padding: var(--spacing-sm) var(--spacing-md);
  background: var(--color-surface);
  border-bottom: 1px solid var(--color-border);
  position: sticky;
  top: 0;
  z-index: 90;
  height: var(--header-height);
}

.mobile-header .logo-text {
  font-size: var(--font-size-lg);
  font-weight: 700;
  color: var(--color-primary);
}

.mobile-header .header-actions {
  display: flex;
  gap: var(--spacing-sm);
}

/* ---- Patient Panel ---- */
.patient-panel {
  background: var(--color-surface);
  border-bottom: 2px solid var(--color-primary);
  padding: var(--spacing-md);
  position: sticky;
  top: var(--header-height);
  z-index: 80;
  box-shadow: var(--shadow-sm);
}

.patient-panel-toggle {
  display: flex;
  align-items: center;
  justify-content: space-between;
  cursor: pointer;
  padding: var(--spacing-xs) 0;
}

.patient-panel-toggle h3 {
  font-size: var(--font-size-sm);
  color: var(--color-primary);
  font-weight: 600;
}

.patient-panel-summary {
  display: flex;
  gap: var(--spacing-md);
  flex-wrap: wrap;
  font-size: var(--font-size-sm);
  color: var(--color-text-secondary);
}

.patient-panel-summary .tag {
  background: var(--color-primary-bg);
  color: var(--color-primary);
  padding: 2px 8px;
  border-radius: 12px;
  font-weight: 500;
  font-size: var(--font-size-xs);
}

.patient-panel-body {
  display: none;
  padding-top: var(--spacing-md);
}

.patient-panel-body.expanded {
  display: block;
}

.patient-fields {
  display: grid;
  grid-template-columns: 1fr 1fr;
  gap: var(--spacing-sm);
}

.patient-fields .field-full {
  grid-column: 1 / -1;
}

/* ---- Bottom Navigation (Mobile) ---- */
.bottom-nav {
  display: flex;
  position: fixed;
  bottom: 0;
  left: 0;
  right: 0;
  height: var(--bottom-nav-height);
  background: var(--color-surface);
  border-top: 1px solid var(--color-border);
  z-index: 100;
  box-shadow: 0 -2px 8px rgba(0, 0, 0, 0.08);
  padding-bottom: env(safe-area-inset-bottom, 0);
}

.bottom-nav a {
  flex: 1;
  display: flex;
  flex-direction: column;
  align-items: center;
  justify-content: center;
  gap: 2px;
  color: var(--color-text-muted);
  font-size: var(--font-size-xs);
  font-weight: 500;
  text-decoration: none;
  transition: color var(--transition-fast);
  min-width: 0;
  padding: var(--spacing-xs);
  -webkit-tap-highlight-color: transparent;
}

.bottom-nav a .nav-icon {
  font-size: 22px;
  line-height: 1;
}

.bottom-nav a span {
  overflow: hidden;
  text-overflow: ellipsis;
  white-space: nowrap;
  max-width: 100%;
}

.bottom-nav a:hover,
.bottom-nav a.active {
  color: var(--color-primary);
  text-decoration: none;
}

.bottom-nav a.active::after {
  content: '';
  position: absolute;
  top: 0;
  left: 25%;
  right: 25%;
  height: 2px;
  background: var(--color-primary);
  border-radius: 0 0 2px 2px;
}

.bottom-nav a {
  position: relative;
}

/* ---- Page Sections ---- */
.page-section {
  display: none;
  padding: var(--spacing-md);
  max-width: 900px;
  margin: 0 auto;
  animation: fadeIn 200ms ease;
}

.page-section.active {
  display: block;
}

@keyframes fadeIn {
  from { opacity: 0; transform: translateY(4px); }
  to { opacity: 1; transform: translateY(0); }
}

.page-header {
  margin-bottom: var(--spacing-lg);
}

.page-header h2 {
  margin-bottom: var(--spacing-xs);
}

.page-header p {
  color: var(--color-text-secondary);
  font-size: var(--font-size-sm);
}

/* ---- Home / Dashboard Tiles ---- */
.dashboard-grid {
  display: grid;
  grid-template-columns: repeat(2, 1fr);
  gap: var(--spacing-md);
  margin-top: var(--spacing-md);
}

.dash-tile {
  background: var(--color-surface);
  border: 1px solid var(--color-border);
  border-radius: var(--border-radius-lg);
  padding: var(--spacing-lg);
  text-align: center;
  cursor: pointer;
  transition: all var(--transition-base);
  text-decoration: none;
  color: var(--color-text);
  display: flex;
  flex-direction: column;
  align-items: center;
  gap: var(--spacing-sm);
  min-height: 120px;
  justify-content: center;
  box-shadow: var(--shadow-card);
}

.dash-tile:hover {
  transform: translateY(-2px);
  box-shadow: var(--shadow-md);
  border-color: var(--color-primary-light);
  text-decoration: none;
}

.dash-tile .tile-icon {
  font-size: 32px;
  line-height: 1;
}

.dash-tile .tile-label {
  font-weight: 600;
  font-size: var(--font-size-sm);
}

.dash-tile .tile-desc {
  font-size: var(--font-size-xs);
  color: var(--color-text-muted);
}

.dash-tile.tile-emergency {
  border-color: var(--severity-contraindicated);
  background: var(--severity-contraindicated-bg);
}

.dash-tile.tile-emergency .tile-icon {
  color: var(--severity-contraindicated);
}

/* ---- Cards ---- */
.card {
  background: var(--color-surface);
  border: 1px solid var(--color-border);
  border-radius: var(--border-radius-lg);
  box-shadow: var(--shadow-card);
  margin-bottom: var(--spacing-md);
  overflow: hidden;
}

.card-header {
  padding: var(--spacing-md);
  border-bottom: 1px solid var(--color-border-light);
  display: flex;
  align-items: center;
  justify-content: space-between;
}

.card-header h3 {
  font-size: var(--font-size-base);
}

.card-body {
  padding: var(--spacing-md);
}

.card-footer {
  padding: var(--spacing-sm) var(--spacing-md);
  border-top: 1px solid var(--color-border-light);
  background: var(--color-surface-alt);
  font-size: var(--font-size-sm);
}

/* Drug card specific */
.drug-card {
  border-left: 4px solid var(--color-primary);
}

.drug-card.severity-contraindicated { border-left-color: var(--severity-contraindicated); }
.drug-card.severity-major { border-left-color: var(--severity-major); }
.drug-card.severity-moderate { border-left-color: var(--severity-moderate); }
.drug-card.severity-minor { border-left-color: var(--severity-minor); }
.drug-card.severity-safe { border-left-color: var(--severity-safe); }

.drug-card-expandable {
  cursor: pointer;
}

.drug-card-details {
  display: none;
  padding: var(--spacing-md);
  border-top: 1px solid var(--color-border-light);
  background: var(--color-surface-alt);
}

.drug-card-details.expanded {
  display: block;
}

/* ---- Form Elements ---- */
.form-group {
  margin-bottom: var(--spacing-md);
}

.form-group label {
  display: block;
  font-size: var(--font-size-sm);
  font-weight: 600;
  margin-bottom: var(--spacing-xs);
  color: var(--color-text-secondary);
}

.form-input,
.form-select,
.form-textarea {
  width: 100%;
  padding: 10px 12px;
  font-size: var(--font-size-base);
  font-family: var(--font-family);
  border: 1px solid var(--color-border);
  border-radius: var(--border-radius);
  background: var(--color-surface);
  color: var(--color-text);
  transition: border-color var(--transition-fast), box-shadow var(--transition-fast);
  appearance: none;
  -webkit-appearance: none;
}

.form-input:focus,
.form-select:focus,
.form-textarea:focus {
  outline: none;
  border-color: var(--color-primary);
  box-shadow: 0 0 0 3px rgba(13, 110, 138, 0.15);
}

.form-input::placeholder {
  color: var(--color-text-muted);
}

.form-select {
  background-image: url("data:image/svg+xml,%3Csvg xmlns='http://www.w3.org/2000/svg' width='12' height='12' viewBox='0 0 12 12'%3E%3Cpath fill='%235a6a7e' d='M6 8L1 3h10z'/%3E%3C/svg%3E");
  background-repeat: no-repeat;
  background-position: right 12px center;
  padding-right: 36px;
}

.form-textarea {
  resize: vertical;
  min-height: 80px;
}

.form-hint {
  font-size: var(--font-size-xs);
  color: var(--color-text-muted);
  margin-top: var(--spacing-xs);
}

.form-error {
  font-size: var(--font-size-xs);
  color: var(--color-danger);
  margin-top: var(--spacing-xs);
}

.input-group {
  display: flex;
  gap: 0;
}

.input-group .form-input {
  border-radius: var(--border-radius) 0 0 var(--border-radius);
}

.input-group .input-addon {
  padding: 10px 12px;
  background: var(--color-surface-alt);
  border: 1px solid var(--color-border);
  border-left: none;
  border-radius: 0 var(--border-radius) var(--border-radius) 0;
  font-size: var(--font-size-sm);
  color: var(--color-text-secondary);
  white-space: nowrap;
  display: flex;
  align-items: center;
}

.toggle-group {
  display: inline-flex;
  border: 1px solid var(--color-border);
  border-radius: var(--border-radius);
  overflow: hidden;
}

.toggle-group button {
  padding: 8px 16px;
  border: none;
  background: var(--color-surface);
  color: var(--color-text-secondary);
  font-size: var(--font-size-sm);
  font-weight: 500;
  cursor: pointer;
  transition: all var(--transition-fast);
  font-family: var(--font-family);
}

.toggle-group button:not(:last-child) {
  border-right: 1px solid var(--color-border);
}

.toggle-group button.active {
  background: var(--color-primary);
  color: white;
}

.checkbox-group,
.radio-group {
  display: flex;
  flex-direction: column;
  gap: var(--spacing-sm);
}

.checkbox-label,
.radio-label {
  display: flex;
  align-items: center;
  gap: var(--spacing-sm);
  cursor: pointer;
  font-size: var(--font-size-sm);
}

/* Multi-select (conditions) */
.multi-select {
  position: relative;
}

.multi-select-tags {
  display: flex;
  flex-wrap: wrap;
  gap: var(--spacing-xs);
  padding: 6px;
  min-height: 42px;
  border: 1px solid var(--color-border);
  border-radius: var(--border-radius);
  background: var(--color-surface);
  cursor: text;
}

.multi-select-tag {
  display: inline-flex;
  align-items: center;
  gap: 4px;
  padding: 2px 8px;
  background: var(--color-primary-bg);
  color: var(--color-primary);
  border-radius: 12px;
  font-size: var(--font-size-xs);
  font-weight: 500;
}

.multi-select-tag .remove-tag {
  cursor: pointer;
  font-weight: 700;
  opacity: 0.7;
}

.multi-select-tag .remove-tag:hover {
  opacity: 1;
}

.multi-select-dropdown {
  position: absolute;
  top: 100%;
  left: 0;
  right: 0;
  background: var(--color-surface);
  border: 1px solid var(--color-border);
  border-radius: var(--border-radius);
  box-shadow: var(--shadow-lg);
  max-height: 200px;
  overflow-y: auto;
  z-index: 50;
  display: none;
}

.multi-select-dropdown.open {
  display: block;
}

.multi-select-option {
  padding: 8px 12px;
  cursor: pointer;
  font-size: var(--font-size-sm);
}

.multi-select-option:hover {
  background: var(--color-primary-bg);
}

/* ---- Buttons ---- */
.btn {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  gap: var(--spacing-sm);
  padding: 10px 20px;
  font-size: var(--font-size-sm);
  font-weight: 600;
  font-family: var(--font-family);
  border: 1px solid transparent;
  border-radius: var(--border-radius);
  cursor: pointer;
  transition: all var(--transition-fast);
  min-height: 44px;
  min-width: 44px;
  -webkit-tap-highlight-color: transparent;
  text-decoration: none;
  line-height: 1.2;
}

.btn:hover {
  text-decoration: none;
}

.btn-primary {
  background: var(--color-primary);
  color: white;
}
.btn-primary:hover {
  background: var(--color-primary-dark);
}

.btn-secondary {
  background: var(--color-surface);
  color: var(--color-text);
  border-color: var(--color-border);
}
.btn-secondary:hover {
  background: var(--color-surface-alt);
}

.btn-accent {
  background: var(--color-accent);
  color: white;
}
.btn-accent:hover {
  background: var(--color-accent-dark);
}

.btn-danger {
  background: var(--color-danger);
  color: white;
}
.btn-danger:hover {
  background: #b91c1c;
}

.btn-ghost {
  background: transparent;
  color: var(--color-text-secondary);
  padding: 8px;
}
.btn-ghost:hover {
  background: var(--color-surface-alt);
  color: var(--color-text);
}

.btn-sm {
  padding: 6px 12px;
  font-size: var(--font-size-xs);
  min-height: 32px;
}

.btn-lg {
  padding: 14px 28px;
  font-size: var(--font-size-base);
}

.btn-block {
  width: 100%;
}

.btn:disabled {
  opacity: 0.5;
  cursor: not-allowed;
}

.btn-group {
  display: flex;
  gap: var(--spacing-sm);
  flex-wrap: wrap;
}

/* Icon button (for header actions etc) */
.icon-btn {
  display: inline-flex;
  align-items: center;
  justify-content: center;
  width: 40px;
  height: 40px;
  border: none;
  border-radius: var(--border-radius);
  background: transparent;
  color: var(--color-text-secondary);
  cursor: pointer;
  font-size: var(--font-size-lg);
  transition: all var(--transition-fast);
  -webkit-tap-highlight-color: transparent;
}

.icon-btn:hover {
  background: var(--color-surface-alt);
  color: var(--color-text);
}

/* ---- Auto-suggest / Search ---- */
.search-container {
  position: relative;
}

.search-input-wrap {
  position: relative;
}

.search-input-wrap .search-icon {
  position: absolute;
  left: 12px;
  top: 50%;
  transform: translateY(-50%);
  color: var(--color-text-muted);
  pointer-events: none;
}

.search-input-wrap .form-input {
  padding-left: 38px;
}

.autosuggest-list {
  position: absolute;
  top: 100%;
  left: 0;
  right: 0;
  background: var(--color-surface);
  border: 1px solid var(--color-border);
  border-top: none;
  border-radius: 0 0 var(--border-radius) var(--border-radius);
  box-shadow: var(--shadow-lg);
  max-height: 280px;
  overflow-y: auto;
  z-index: 50;
  display: none;
}

.autosuggest-list.open {
  display: block;
}

.autosuggest-item {
  padding: 10px 12px;
  cursor: pointer;
  font-size: var(--font-size-sm);
  display: flex;
  justify-content: space-between;
  align-items: center;
  border-bottom: 1px solid var(--color-border-light);
}

.autosuggest-item:hover,
.autosuggest-item.highlighted {
  background: var(--color-primary-bg);
}

.autosuggest-item .drug-name {
  font-weight: 600;
}

.autosuggest-item .drug-class {
  font-size: var(--font-size-xs);
  color: var(--color-text-muted);
}

/* ---- Severity Badges ---- */
.severity-badge {
  display: inline-flex;
  align-items: center;
  padding: 2px 10px;
  border-radius: 12px;
  font-size: var(--font-size-xs);
  font-weight: 600;
  text-transform: uppercase;
  letter-spacing: 0.02em;
}

.severity-badge.contraindicated {
  background: var(--severity-contraindicated-bg);
  color: var(--severity-contraindicated);
}
.severity-badge.major {
  background: var(--severity-major-bg);
  color: var(--severity-major);
}
.severity-badge.moderate {
  background: var(--severity-moderate-bg);
  color: var(--severity-moderate);
}
.severity-badge.minor {
  background: var(--severity-minor-bg);
  color: var(--severity-minor);
}
.severity-badge.safe {
  background: var(--severity-safe-bg);
  color: var(--severity-safe);
}

/* ---- Range Slider ---- */
.dose-slider-wrap {
  margin: var(--spacing-md) 0;
}

.dose-slider-wrap label {
  display: flex;
  justify-content: space-between;
  align-items: center;
  font-size: var(--font-size-sm);
  margin-bottom: var(--spacing-xs);
}

.dose-slider-wrap input[type="range"] {
  width: 100%;
  height: 6px;
  border-radius: 3px;
  background: var(--color-border);
  outline: none;
  -webkit-appearance: none;
}

.dose-slider-wrap input[type="range"]::-webkit-slider-thumb {
  -webkit-appearance: none;
  width: 22px;
  height: 22px;
  border-radius: 50%;
  background: var(--color-primary);
  cursor: pointer;
  border: 3px solid white;
  box-shadow: var(--shadow-sm);
}

.dose-slider-wrap .slider-labels {
  display: flex;
  justify-content: space-between;
  font-size: var(--font-size-xs);
  color: var(--color-text-muted);
  margin-top: 2px;
}

/* ---- Results Display ---- */
.result-box {
  background: var(--color-primary-bg);
  border: 1px solid var(--color-primary);
  border-radius: var(--border-radius-lg);
  padding: var(--spacing-lg);
  margin: var(--spacing-md) 0;
}

.result-box .result-label {
  font-size: var(--font-size-xs);
  color: var(--color-primary);
  text-transform: uppercase;
  font-weight: 600;
  letter-spacing: 0.05em;
}

.result-box .result-value {
  font-size: var(--font-size-2xl);
  font-weight: 700;
  color: var(--color-primary-dark);
}

.result-box .result-unit {
  font-size: var(--font-size-sm);
  color: var(--color-text-secondary);
}

.result-grid {
  display: grid;
  grid-template-columns: repeat(auto-fit, minmax(140px, 1fr));
  gap: var(--spacing-md);
}

.formula-display {
  background: var(--color-surface-alt);
  border: 1px solid var(--color-border);
  border-radius: var(--border-radius);
  padding: var(--spacing-md);
  font-family: var(--font-mono);
  font-size: var(--font-size-sm);
  margin: var(--spacing-sm) 0;
  overflow-x: auto;
  color: var(--color-text-secondary);
}

/* ---- Interaction Matrix ---- */
.interaction-matrix {
  overflow-x: auto;
  margin: var(--spacing-md) 0;
}

.interaction-matrix table {
  border-collapse: collapse;
  width: 100%;
  font-size: var(--font-size-sm);
}

.interaction-matrix th,
.interaction-matrix td {
  padding: 8px;
  border: 1px solid var(--color-border);
  text-align: center;
}

.interaction-matrix th {
  background: var(--color-surface-alt);
  font-weight: 600;
  font-size: var(--font-size-xs);
}

.interaction-cell {
  cursor: pointer;
  min-width: 40px;
  min-height: 40px;
}

.interaction-cell.contraindicated { background: var(--severity-contraindicated-bg); }
.interaction-cell.major { background: var(--severity-major-bg); }
.interaction-cell.moderate { background: var(--severity-moderate-bg); }
.interaction-cell.minor { background: var(--severity-minor-bg); }
.interaction-cell.safe { background: var(--severity-safe-bg); }
.interaction-cell.none { background: var(--color-surface); }

/* ---- Interaction List ---- */
.interaction-list {
  display: flex;
  flex-direction: column;
  gap: var(--spacing-sm);
}

.interaction-item {
  border: 1px solid var(--color-border);
  border-radius: var(--border-radius);
  overflow: hidden;
}

.interaction-item-header {
  display: flex;
  align-items: center;
  justify-content: space-between;
  padding: var(--spacing-sm) var(--spacing-md);
  cursor: pointer;
  gap: var(--spacing-sm);
}

.interaction-item-detail {
  display: none;
  padding: var(--spacing-md);
  border-top: 1px solid var(--color-border-light);
  background: var(--color-surface-alt);
  font-size: var(--font-size-sm);
}

.interaction-item-detail.expanded {
  display: block;
}

/* ---- Tables ---- */
.data-table {
  width: 100%;
  border-collapse: collapse;
  font-size: var(--font-size-sm);
}

.data-table th,
.data-table td {
  padding: 10px 12px;
  text-align: left;
  border-bottom: 1px solid var(--color-border-light);
}

.data-table th {
  font-weight: 600;
  color: var(--color-text-secondary);
  font-size: var(--font-size-xs);
  text-transform: uppercase;
  letter-spacing: 0.03em;
  background: var(--color-surface-alt);
  position: sticky;
  top: 0;
}

.data-table tr:hover td {
  background: var(--color-surface-alt);
}

/* ---- Tabs ---- */
.tabs {
  display: flex;
  border-bottom: 2px solid var(--color-border);
  overflow-x: auto;
  gap: 0;
  -webkit-overflow-scrolling: touch;
}

.tab-btn {
  padding: 10px 16px;
  border: none;
  background: transparent;
  font-size: var(--font-size-sm);
  font-weight: 500;
  color: var(--color-text-muted);
  cursor: pointer;
  white-space: nowrap;
  border-bottom: 2px solid transparent;
  margin-bottom: -2px;
  transition: all var(--transition-fast);
  font-family: var(--font-family);
  min-height: 44px;
}

.tab-btn:hover {
  color: var(--color-text);
}

.tab-btn.active {
  color: var(--color-primary);
  border-bottom-color: var(--color-primary);
  font-weight: 600;
}

.tab-content {
  display: none;
  padding: var(--spacing-md) 0;
}

.tab-content.active {
  display: block;
}

/* ---- Modals ---- */
.modal-overlay {
  display: none;
  position: fixed;
  top: 0;
  left: 0;
  right: 0;
  bottom: 0;
  background: rgba(0, 0, 0, 0.5);
  z-index: 200;
  align-items: center;
  justify-content: center;
  padding: var(--spacing-md);
}

.modal-overlay.open {
  display: flex;
}

.modal {
  background: var(--color-surface);
  border-radius: var(--border-radius-lg);
  width: 100%;
  max-width: 520px;
  max-height: 85vh;
  overflow-y: auto;
  box-shadow: var(--shadow-lg);
}

.modal-header {
  display: flex;
  align-items: center;
  justify-content: space-between;
  padding: var(--spacing-md) var(--spacing-lg);
  border-bottom: 1px solid var(--color-border);
}

.modal-header h3 {
  font-size: var(--font-size-lg);
}

.modal-body {
  padding: var(--spacing-lg);
}

.modal-footer {
  padding: var(--spacing-md) var(--spacing-lg);
  border-top: 1px solid var(--color-border);
  display: flex;
  justify-content: flex-end;
  gap: var(--spacing-sm);
}

/* ---- Alerts ---- */
.alert {
  padding: var(--spacing-md);
  border-radius: var(--border-radius);
  font-size: var(--font-size-sm);
  margin-bottom: var(--spacing-md);
  display: flex;
  align-items: flex-start;
  gap: var(--spacing-sm);
}

.alert-info {
  background: var(--severity-minor-bg);
  border: 1px solid var(--color-info);
  color: var(--color-info);
}

.alert-success {
  background: var(--severity-safe-bg);
  border: 1px solid var(--color-success);
  color: var(--color-success);
}

.alert-warning {
  background: var(--severity-moderate-bg);
  border: 1px solid var(--color-warning);
  color: var(--color-warning);
}

.alert-danger {
  background: var(--severity-contraindicated-bg);
  border: 1px solid var(--color-danger);
  color: var(--color-danger);
}

/* ---- Loading ---- */
.spinner {
  display: inline-block;
  width: 24px;
  height: 24px;
  border: 3px solid var(--color-border);
  border-top-color: var(--color-primary);
  border-radius: 50%;
  animation: spin 0.8s linear infinite;
}

.spinner-lg {
  width: 40px;
  height: 40px;
  border-width: 4px;
}

@keyframes spin {
  to { transform: rotate(360deg); }
}

.loading-overlay {
  display: flex;
  flex-direction: column;
  align-items: center;
  justify-content: center;
  padding: var(--spacing-2xl);
  gap: var(--spacing-md);
  color: var(--color-text-muted);
}

/* ---- Toast Notifications ---- */
.toast-container {
  position: fixed;
  top: var(--spacing-md);
  right: var(--spacing-md);
  z-index: 300;
  display: flex;
  flex-direction: column;
  gap: var(--spacing-sm);
}

.toast {
  background: var(--color-surface);
  border: 1px solid var(--color-border);
  border-radius: var(--border-radius);
  padding: var(--spacing-sm) var(--spacing-md);
  box-shadow: var(--shadow-lg);
  font-size: var(--font-size-sm);
  display: flex;
  align-items: center;
  gap: var(--spacing-sm);
  animation: slideIn 200ms ease;
  max-width: 360px;
}

.toast.toast-error { border-left: 4px solid var(--color-danger); }
.toast.toast-success { border-left: 4px solid var(--color-success); }
.toast.toast-warning { border-left: 4px solid var(--color-warning); }

@keyframes slideIn {
  from { opacity: 0; transform: translateX(20px); }
  to { opacity: 1; transform: translateX(0); }
}

/* ---- Protocol Steps ---- */
.protocol-steps {
  display: flex;
  flex-direction: column;
  gap: 0;
  position: relative;
}

.protocol-step {
  display: flex;
  gap: var(--spacing-md);
  position: relative;
  padding-bottom: var(--spacing-md);
}

.protocol-step::before {
  content: '';
  position: absolute;
  left: 15px;
  top: 32px;
  bottom: 0;
  width: 2px;
  background: var(--color-border);
}

.protocol-step:last-child::before {
  display: none;
}

.step-number {
  width: 32px;
  height: 32px;
  border-radius: 50%;
  background: var(--color-primary);
  color: white;
  display: flex;
  align-items: center;
  justify-content: center;
  font-size: var(--font-size-sm);
  font-weight: 700;
  flex-shrink: 0;
}

.step-content {
  flex: 1;
  background: var(--color-surface);
  border: 1px solid var(--color-border);
  border-radius: var(--border-radius);
  padding: var(--spacing-md);
}

/* ---- Stock / Formulary status ---- */
.stock-indicator {
  display: inline-flex;
  align-items: center;
  gap: 4px;
  font-size: var(--font-size-xs);
  font-weight: 600;
}

.stock-dot {
  width: 8px;
  height: 8px;
  border-radius: 50%;
}

.stock-in .stock-dot { background: var(--color-success); }
.stock-low .stock-dot { background: var(--color-warning); }
.stock-out .stock-dot { background: var(--color-danger); }
.stock-expired .stock-dot { background: var(--color-danger); }

.expiry-alert {
  color: var(--color-danger);
  font-size: var(--font-size-xs);
  font-weight: 600;
}

/* ---- Active Drug List ---- */
.active-drug-list {
  display: flex;
  flex-wrap: wrap;
  gap: var(--spacing-xs);
  margin: var(--spacing-sm) 0;
}

.active-drug-chip {
  display: inline-flex;
  align-items: center;
  gap: 4px;
  padding: 4px 10px;
  border-radius: 16px;
  background: var(--color-primary-bg);
  color: var(--color-primary);
  font-size: var(--font-size-xs);
  font-weight: 600;
}

.active-drug-chip .remove-chip {
  cursor: pointer;
  margin-left: 2px;
  opacity: 0.7;
}

.active-drug-chip .remove-chip:hover {
  opacity: 1;
}

/* ---- Utility ---- */
.text-center { text-align: center; }
.text-muted { color: var(--color-text-muted); }
.text-danger { color: var(--color-danger); }
.text-success { color: var(--color-success); }
.text-sm { font-size: var(--font-size-sm); }
.text-xs { font-size: var(--font-size-xs); }
.text-mono { font-family: var(--font-mono); }
.font-bold { font-weight: 700; }
.mt-sm { margin-top: var(--spacing-sm); }
.mt-md { margin-top: var(--spacing-md); }
.mt-lg { margin-top: var(--spacing-lg); }
.mb-sm { margin-bottom: var(--spacing-sm); }
.mb-md { margin-bottom: var(--spacing-md); }
.mb-lg { margin-bottom: var(--spacing-lg); }
.hidden { display: none !important; }
.flex { display: flex; }
.flex-between { display: flex; justify-content: space-between; align-items: center; }
.flex-center { display: flex; align-items: center; justify-content: center; }
.gap-sm { gap: var(--spacing-sm); }
.gap-md { gap: var(--spacing-md); }

.sr-only {
  position: absolute;
  width: 1px;
  height: 1px;
  padding: 0;
  margin: -1px;
  overflow: hidden;
  clip: rect(0, 0, 0, 0);
  border: 0;
}

/* ---- Desktop Layout (768px+) ---- */
@media (min-width: 768px) {
  .sidebar {
    display: flex;
    flex-direction: column;
  }

  .mobile-header {
    display: none;
  }

  .bottom-nav {
    display: none;
  }

  .main-content {
    margin-left: var(--sidebar-width);
    padding-bottom: var(--spacing-xl);
  }

  .patient-panel {
    top: 0;
  }

  .patient-fields {
    grid-template-columns: repeat(4, 1fr);
  }

  .dashboard-grid {
    grid-template-columns: repeat(3, 1fr);
  }

  .page-section {
    padding: var(--spacing-lg) var(--spacing-xl);
  }
}

/* ---- Large Desktop (1024px+) ---- */
@media (min-width: 1024px) {
  .page-section {
    max-width: 1000px;
  }

  .dashboard-grid {
    grid-template-columns: repeat(3, 1fr);
    gap: var(--spacing-lg);
  }

  .result-grid {
    grid-template-columns: repeat(4, 1fr);
  }
}

/* ---- Print Styles ---- */
@media print {
  .sidebar,
  .bottom-nav,
  .mobile-header,
  .patient-panel,
  .no-print {
    display: none !important;
  }

  .main-content {
    margin-left: 0 !important;
    padding: 0 !important;
  }

  .page-section {
    display: block !important;
    max-width: 100% !important;
    padding: 0 !important;
  }

  body {
    background: white;
    color: black;
    font-size: 12pt;
  }

  .card {
    box-shadow: none;
    border: 1px solid #ccc;
    break-inside: avoid;
  }

  .emergency-sheet {
    page-break-before: always;
  }

  .emergency-sheet h2 {
    text-align: center;
    font-size: 18pt;
    margin-bottom: 12pt;
    border-bottom: 2px solid black;
    padding-bottom: 6pt;
  }

  .emergency-sheet table {
    width: 100%;
    border-collapse: collapse;
    font-size: 10pt;
  }

  .emergency-sheet th,
  .emergency-sheet td {
    border: 1px solid #333;
    padding: 4pt 6pt;
  }

  .emergency-sheet th {
    background: #eee !important;
    -webkit-print-color-adjust: exact;
    print-color-adjust: exact;
  }

  .severity-badge {
    border: 1px solid currentColor;
    -webkit-print-color-adjust: exact;
    print-color-adjust: exact;
  }
}